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Nicotine. The life saving miracle natural substance. Pharma trying to remove by 2030
(03-19-2026, 01:12 PM)andy06shake Wrote: Sounds like another predictable handy ""anecdote.""  Spin

https://pmc.ncbi.nlm.nih.gov/articles/PMC1939993/
https://actchealth.com/blogs/nicotine-gu...autious-of
https://www.verywellmind.com/addicted-to...at-2825031

Im sure you know best.

I mean, the gum is less harmful than tobacco.

But addictive nonetheless.

All anecdotal tales told to frighten the meek away from Nicotine. If addictive at all. Nicotine is a very weak addiction. Science proves it is only the smoke and additives that form the powerful tobacco addiction.  Yes I'm positive I always know what's best.
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(03-19-2026, 12:53 PM)andy06shake Wrote: There's no credible medical evidence nicotine prevents or treats rabies Knows

If anything, relying on that idea is downright dangerous.

Rabies is almost always fatal once the symptoms appear.

Imagine some poor sod actually listens to these quacks....oh, wait...

How do we know that the Rabies VAX actually has ever worked. Since they claim  it only works before any symptoms have occurred?   Lol
Quote:AI Overview  

There is no reliable, immediate test to determine if a human needs the rabies vaccine after an exposure; decisions are based on risk assessment (animal type, behavior, and vaccination status). If exposure is suspected, immediate post-exposure prophylaxis (PEP)—vaccines and sometimes immunoglobulin—is required, as testing is not used to delay life-saving treatment.
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(03-19-2026, 01:42 PM)Knows Wrote: How d we know that the Rabies VAX actually has ever worked. Since they claim  it only works before any symptoms have occurred?   Lol

I imagine the difference in outcomes is strong proof that it works, Knows.  Saint2
"Yet so it is, we see the illiterate bulk of mankind that walk the high-road of plain common sense, and are governed by the dictates of nature, for the most part easy and undisturbed. To them nothing that is familiar appears unaccountable or difficult to comprehend."
(03-19-2026, 01:47 PM)andy06shake Wrote: I imagine the difference in outcomes is strong proof that it works, Knows.  Saint2

No. Most of the time they are giving the Vaccine to uninfected patients as a precaution. If they die they simply claim it was too late. How would you know any difference in  outcomes? Since there is no reliable tests to know if you are actually infected? 

It's even possible you could contract the rabies or another disease from a tainted vaccine.
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(03-19-2026, 02:01 PM)Knows Wrote: No. Most of the time they are giving the Vaccine to uninfected patients as a precaution. If they die they simply claim it was too late. How would you know any difference in  outcomes? Since there is no reliable tests to know if you are actually infected? 

It's even possible you could contract the rabies or another disease from a tainted vaccine.

Nope, sorry, but that falls apart pretty fast.

Rabies vaccines aren't given randomly.

They're used after a known exposure.

Like when you are bitten by a wild animal, and the risk is already high.

Outcomes are pretty clear, untreated rabies is fatal.

People who receive a vaccine overwhelmingly survive...
"Yet so it is, we see the illiterate bulk of mankind that walk the high-road of plain common sense, and are governed by the dictates of nature, for the most part easy and undisturbed. To them nothing that is familiar appears unaccountable or difficult to comprehend."
(03-19-2026, 02:01 PM)Knows Wrote: No. Most of the time they are giving the Vaccine to uninfected patients as a precaution. If they die they simply claim it was too late. How would you know any difference in  outcomes? Since there is no reliable tests to know if you are actually infected? 

It's even possible you could contract the rabies or another disease from a tainted vaccine.

That's a total fabrication. 

Healthcare professionals don't just hand out rabies vaccines to random people for fun?!?!?



 
"Denial is a common tactic that substitutes deliberate ignorance for thoughtful planning." 
Charles Tremper
(03-19-2026, 12:53 PM)andy06shake Wrote: There's no credible medical evidence nicotine prevents or treats rabies Knows

If anything, relying on that idea is downright dangerous.

Rabies is almost always fatal once the symptoms appear.

Imagine some poor sod actually listens to these quacks....oh, wait...

I think 'Knows' may have been confused as to what the actual study found. It's a very difficult and complex study to follow, just saying. It found this:

"nAChRs are known to modulate behaviors including aggression, attention, mood, and impulsivity. Nicotine and other drugs targeting nAChRs can reduce offensive, defensive, and predatory aggression in animal models [89]. Correspondingly, in human laboratory and clinical settings, nicotine may reduce aggressive behavior [909192939495], and the α7 nAChR subtype may be a critical component to modulating this aggressive behavior. The α7 nAChR is necessary for the anti-aggressive or ‘serenic’ effects of systemic administration of nicotine, and an α7 nAChR partial agonist (GTS-21) can reestablish this serenic nicotinic effect [46]"

https://pmc.ncbi.nlm.nih.gov/articles/PMC9450143/
"The only journey is the one within."
(03-20-2026, 06:50 AM)quintessentone Wrote: I think 'Knows' may have been confused as to what the actual study found. It's a very difficult and complex study to follow, just saying. It found this:

"nAChRs are known to modulate behaviors including aggression, attention, mood, and impulsivity. Nicotine and other drugs targeting nAChRs can reduce offensive, defensive, and predatory aggression in animal models [89]. Correspondingly, in human laboratory and clinical settings, nicotine may reduce aggressive behavior [909192939495], and the α7 nAChR subtype may be a critical component to modulating this aggressive behavior. The α7 nAChR is necessary for the anti-aggressive or ‘serenic’ effects of systemic administration of nicotine, and an α7 nAChR partial agonist (GTS-21) can reestablish this serenic nicotinic effect [46]"

https://pmc.ncbi.nlm.nih.gov/articles/PMC9450143/

I don't think there is any doubt that Nicotine temporarily makes us feel more at ease, Quint.

It's probably the reason people choose to smoke or become addicted in the first place. 

Aside from peer pressure, of course.  

But I'm led to believe in the long run.

It actually increases stress and anxiety by causing withdrawal symptoms(he says whilst sucking on a vape).

Aka the irritability and/or nervousness that can develop between fags. 

I don't doubt that Nicotine exhibits behavior modification properties.

Most drugs that we choose to consume for pleasure tick that box.

But it's unfortunately not some sort of miracle cure for all manner of different ailments like Knows would have us believe.

He's not confused mate, he also thinks cannabis cures cancer.

Im apt to ponder, knows likes the alternative facts better than the actual ones. 

Which is fine, people are free to entertain whatever they please. 

But it can be very dangerous to punt fake hope and information where terminal diseases are concerned.

The problem being some poor sap may actually listen and disregard the conventional proven treatment.

Which may end up giving them somewhat less time to put their affairs in order and "get ready for the big ride, baby."
"Yet so it is, we see the illiterate bulk of mankind that walk the high-road of plain common sense, and are governed by the dictates of nature, for the most part easy and undisturbed. To them nothing that is familiar appears unaccountable or difficult to comprehend."
(03-20-2026, 07:46 AM)andy06shake Wrote: I don't think there is any doubt that Nicotine temporarily makes us feel more at ease, Quint.

It's probably the reason people choose to smoke or become addicted in the first place. 

Aside from peer pressure, of course.  

But I'm led to believe in the long run.

It actually increases stress and anxiety by causing withdrawal symptoms(he says whilst sucking on a vape).

Aka the irritability and/or nervousness that can develop between fags. 

I don't doubt that it exhibits behavior modification properties.

Most drugs that we choose to consume for pleasure tick that box.

But it's unfortunately not some sort of miracle cure for all manner of different ailments like Knows would have us believe.

He's not confused mate, he also thinks cannabis cures cancer.

Im apt to ponder, knows likes the alternative facts better than the actual ones. 

Which is fine, people are free to entertain whatever they please. 

But it can be very dangerous to punt fake hope and information where terminal diseases are concerned.

The problem being some poor sap may actually listen and disregard the conventional proven treatment.

Which may end up giving them somewhat less time to put their affairs in order and "get ready for the big ride, baby."

I agree about the fake hope illusion but it is up to us to dive deeper to understand fully what these types of complex research are really showing.

They are at the forefront of separating compounds from many substances and it is quite impressive that they can apply certain actions/reactions to certain symptoms of certain diseases.

Such as the case with the nicotine compound a7 nAChR:

"α7 nicotinic acetylcholine receptors (nAChRs) are not primarily responsible for the addictive effects of nicotine, based on current evidence. 
  • Research indicates that α4β2 nAChRs are the main subtype mediating nicotine's primary reinforcing and addictive properties, including self-administration and conditioned place preference. 
  • In contrast, studies using α7 nAChR knockout mice show no significant difference in nicotine self-administration or conditioned place preference, suggesting α7 receptors are not essential for nicotine reward or addiction reinforcement. 
  • However, α7 nAChRs play a role in nicotine withdrawal symptoms.  Mice lacking the α7 subunit exhibit decreased somatic signs of withdrawal, indicating involvement in withdrawal but not addiction itself. 
  • While α7 receptors are not directly linked to addiction, they are involved in neuroprotection, cognitive enhancement, and modulation of dopamine release in the ventral tegmental area (VTA), which may indirectly influence addiction-related behaviors. 
In summary, α7 nAChRs are not directly addictive, but they contribute to withdrawal and may be promising therapeutic targets for reducing relapse rather than treating the core addictive drive. "

https://pmc.ncbi.nlm.nih.gov/articles/PMC2766171/

It's great that we can all try to figure out what is really going on to help dispel misinformation from those who can't quite understand what they are reading because we are not at the level of those scientists who are expert in their fields.
"The only journey is the one within."
(03-20-2026, 08:05 AM)quintessentone Wrote: It's great that we can all try to figure out what is really going on to help dispel misinformation from those who can't quite understand what they are reading because we are not at the level of those scientists who are expert in their fields.

Indeed, as long as you don't have a terminal illness and are trying to cure it with Nicotine or Weed alone.

I don't doubt the therapeutic value of the substances or the potential they may have to help. 

Hypocritical for me to suggest otherwise, considering i use both daily myself. 

But they are in no way proven miracles cures.

I'll trust the actual science before some doctor, not doctor, on the likes of Rumble or Bitchute.

Especially when they are also trying to push other health supplements at exorbitant prices.

Each to their own, buddy, thats what i say, but not at the expense or possible demise of others.  Thumbup
"Yet so it is, we see the illiterate bulk of mankind that walk the high-road of plain common sense, and are governed by the dictates of nature, for the most part easy and undisturbed. To them nothing that is familiar appears unaccountable or difficult to comprehend."



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