Nicotine. The life saving miracle natural substance. Pharma trying to remove by 2030

[Kurokage]

You need to go back and re-read comments on page 7 then, and except the actual facts instead of helping some hack pedal 'snake-oil'.

[Knows]

However, substantial evidence exists to suggest that nicotine's reinforcing effects alone are not sufficient to account for the intense addictive properties of tobacco smoking and the high relapse rates among smokers after quitting even when provided nicotine in forms other than tobacco.[sup]8–16[/sup] Further evidence that tobacco dependence entails more than addiction to nicotine includes the drug's limited ability to induce self-administration in animals;[sup]17[/sup] [sup]18[/sup] lack of positive mood effects of pure nicotine in abstinent smokers;[sup]19–21[/sup] lack of findings that nicotine in any other form than tobacco was preferred to placebo in normal smokers;[sup]22[/sup] [sup]23[/sup] de-nicotinised cigarettes were as effective as regular cigarettes, and more than nicotine in any other delivery mode, in relieving withdrawal and craving;[sup]24–27[/sup] and essential role of non-nicotine factors in cigarette addiction.[sup]24[/sup] [sup]28[/sup]

 

Tobacco manufacturers modified the design of products by directly adding constituents to cigarettes that stimulate gustatory, tactile and olfactory nerve receptors and create chemosensory effects that could enhance elasticity in nicotine dosing as well as strengthen sensory cueing to optimise the ‘pleasure’ in smoking.[sup]38[/sup] [sup]42–51[/sup] Pyrazines, a class of chemosensory agents, comprise 15 of the 599 compounds on the list of cigarette ingredients provided by manufacturers to the US Department of Health and Human Services in 1994,[sup]52[/sup] 8 of the compounds on the list of additive ingredients provided by manufacturers to the FDA in 2011[sup]53[/sup] and 10 of the compounds presently listed on cigarette manufacturers’ website as cigarette ingredients”[sup]54–56[/sup] (box 1). The present study explores tobacco industry research that first identified pyrazines in tobacco smoke and was followed by the introduction of pyrazines in ‘light’ cigarettes and subsequent incorporation into Marlboro Lights and eventually in many other cigarette brands. It further examines their possible role in abuse potential.

A study of pyrazines in cigarettes and how additives might be used to enhance tobacco addiction

[andy06shake]

I know that the additives in tobacco products are the addictive components. And the smoke itself. Not the Nicotine itself. 
Oh. So you claim you have proof Nicotine is addictive? Why don't you show us? I'm anxious to see your proof. I know both of you are suffering from DOGMA. Chuckle.

Nicotine itself is well-established as the primary addictive substance in tobacco.

Major health authorities and decades of peer-reviewed research consistently conclude that nicotine is inherently addictive Knows. 

If you smoke cigarettes and don't think you are addicted to Nicotine.

Try stopping for a few hours, or a day, and watch those cravings become near unbearable. 




https://pubmed.ncbi.nlm.nih.gov/7724697/
https://nida.nih.gov/publications/resear...-addictive

[rickymouse]

Tell that to Michael J. Fox. When he was diagnosed with Parkinsons, he smoked like a chimney. I don't know if he still does now, but nicotine certainly didn't diminish nor cure him of Parkinsons. I wish people wouldn't spread this nonsense, from some dude who isn't a real doctor and is just spreading conspiracy bullshit to get money from gullible people (not including you in this, just generally speaking). 

I know some people who have long covid who currently smoke. They still have long covid. I just get so annoyed and irritated when I see this garbage. There is no way on God's green earth that there is any snake venom in the covid vaccines. I would have been long since dead, since I got every damn shot. BTW, I have NEVER had covid. What does that tell you? My sister, who refused to get vaccinated, has had it THREE TIMES.

WE do not know if Michael J. Fox would have been worse off if he had not smoked.  But there is some real evidence that Nicotine can slow progression...not cure the disease though, just help to impede it.  Now, there are other chemicals used in tobacco that might also negate the benefit of the Nicotine too.  They add a lot of chemicals to the fields and in production of cigarettes, organic tobacco would be less problematic than commercial cigarettes in added chemistry to the cigarettes.

The wife got vaccinated for covid, I declined it because of my Doctor observed reaction to the flu vaccine and my intollerance to propylene glycol, polyethylene glycol, and polysorbate eighty.  By the way, I smoke, and the tobacco I buy and the cigarettes I used to smoke for decades did not have the propylene glycol in them....I smoke sun grown tobacco now and used to smoke Winstons...neither have that chemistry in them.  I could also smoke the American spirit.  The glycol chemistry makes my lungs feel waterlogged, and shampoos with propylene glycol in them give me hives on my scalp....I also might be more allergic to the glycols in Ice creams than the milk allergy I have. 

I got covid three times, it was not bad, sort of like a cold for me but It make everything taste like that crappy taste from fermented swedish or Norwegian fish my dad used to buy when I was young....I ate it, but did not care for it.  The wife got pretty sick even with her first vaccine, actually she got sick after getting vaccinated and gave the crap to me.  She probably caught it waiting in line at the vaccine place outside.  I did not go in for it.  We had the virus already in maybe may of two thousand twenty, but that was not verified, they did not have tests then but six months later the wife got tested and it was positive, and I probably had it then too, because the food all tasted like that horrible rotted fish.  I love fish....but not that crap.  I also do not like the sauces made from fermented fish...but pickled herring is usually alright...except the more expensive crap which has way too much umami for me.  Got a problem with tyramines in food.

Some people do alright with that vaccine, but when I get vaccines...except for straight tetnus, I get a cytokine storm or bradykin storm and get sicker than a dog.  According to the doctors I talked to and two that observed the reactions, some people have that problem when they stick it into your body, the immune system goes nuts.  The last doctor who witnessed it said beware, and that what he saw could kill me so never take the flu shot again since I never got it bad....the wife hated that I never got much sick from the flu or anything, a day or two of mild symptoms which put her down for days or weeks. 

Everyone is different, but I will not take the vaccine when it has a chemistry...the glycol chemistry...that I know I am very intolerant to.  That glycol intolerance is not that uncommon....and in the release from the CDC they mentioned if you are allergic to any of the ingredients you should not get the covid shot....I listened to what they said, and I read what they wrote.  An intolerance is not the same as an allergy, but both are dangerous.

Since I am allergic or intollerant to the flu shot, people always ask me if I am allergic to eggs, I tell them I love eggs and eat lots of eggs and that always makes them confused, because I have known about the cytokine storm for over thirty years....I was informed that is what I got to the flu shot back then by the doctor and many doctors after that doctor...it is listed on my medical records.  I also cannot take the Dtap,. but I can take the tetnus by itself.

I do have the genetics for parkinson disease and alkolyzing spondylitis and RA.  Adjusted my diet and it really helped get rid of the symptoms I was starting to have.  My cousin died of parkinson disease, my brother was getting crippled from the spondylitis, but I told him how to dampen it, and he is still having issues but the progression has gone way down, and he does not have to take meds and the doctors and specialists are confused as to how he fixed the issue.  He has taken what I told him and altered it to fit his personal condition, I will need to get info on specifics from him if My spondytlitis kicks in.  The wife can't comprehend I can control these things with diet...but I control my epilepsy with diet so something like an autoimmune disease is a piece of cake.  My wife also is on less meds and less bad conditions since I have been cooking.  She has a condition where if she eats meat and vitamin C at the same meal, she gets bad bruises if she just touches her arms...I think that was the Urod genes in her genetics.  Simple, do not drink anything with vitamin c in it when eating red meats....Then it is manageable.  Bacon is not a problem, but steak and eggs is.  She hates when I tell her not to eat things in combinations, but reaps the benefit and it is very noticable if she messes up.  She takes up too much iron, then it does not attach strongly to the red blood  cells, so it makes her bruise easily...vitamin  c makes iron absorption go way up.  This is a problem she has had since I met her...she had to give blood for many years to bring the iron down.  I tell her, have spaghetti without meat...just sauce....she suffers.

[Byrd]

(sorry about weird formatting)

There's plenty of evidence that nicotine causes cancer -- heck, back in the 1940's, cigarettes were known as "cancer sticks" and "coffin nails."  There's also warnings on every single nicotine patch (and chewing tobacco tins, and cigarettes) that nicotine can cause cancer.

Ardis clearly has NO idea what venom is.

"Venom" is a toxin that is delivered by the bite or sting of an animal.  There are conditions caused by the bite/sting of an animal or insect.  Every physician, nurse, firefighter, emergency responder, and EMT knows the difference between venom, poison, and toxin.   Chiropractors aren't taught that.   You can become a board-certified chiropractor by taking online courses and passing an exam.  Chiropractors can't administer vaccines legally or prescribe medicines legally or do surgeries legally -- they have not taken the years and years of coursework and residency to be able to do those things.


Yeah, I get a bit spicy on this topic.

My husband was diagnosed with Parkinson's 10 years ago and am a member of several support groups for spouses on Facebook and other platforms.  We share info on clinical trials, over-the-counter products, vitamins, assistance devices, psychological issues, and so forth.  We also exchange warning info on "snake oil" products.  

Nobody miraculously gets well.  If they did, the news would VERY quickly spread through the community and everyone would be trying it.  We'd all know about it.
 

There is zero evidence in that article that nicotine causes cancer. Read it again. Just anecdotal. No studies at all. Probably the other addictive additives in the tobacco.  Or tar etc. 

Nobody I know of. Knows what causes Parkinson's in every case. Ardis has only stated that It has been induced with venom. And in those cases was reversed with Nicotine.  Some pesticides have venom these days. Look down on the list. Google AI states pesticides as a possible cause.  
 Parkinson's disease is caused by the progressive loss of dopamine-producing neurons in the brain, leading to dopamine deficiency and motor issues. It is likely caused by a combination of genetic mutations, environmental factors, and age-related changes, resulting in the buildup of abnormal proteins called Lewy bodies. Key Causes and Risk Factors

• Environmental Factors: Exposure to pesticides, solvents, or prior head injuries may increase risk.
  
• Lewy Bodies: The buildup of a protein called alpha-synuclein creates "Lewy bodies" in brain cells, which is a hallmark of the disease.
  
• Age: The risk increases with age, with most cases occurring in people 50 or older. 
  

• Brain Cell Death: Nerve cells (neurons) that produce dopamine—a neurotransmitter controlling movement—die or become damaged.
  
• Genetics: Approximately 10–15% of cases have a genetic link. Gene mutations like LRRK2, GBA, PRKN, and SNCA are linked to higher risk.
  

[Knows]

(sorry about weird formatting)

There's plenty of evidence that nicotine causes cancer -- heck, back in the 1940's, cigarettes were known as "cancer sticks" and "coffin nails."  There's also warnings on every single nicotine patch (and chewing tobacco tins, and cigarettes) that nicotine can cause cancer.

Scientific and health organizations distinguish between the risks of nicotine itself and the carcinogenic compounds found in tobacco products. Whilecigarettes and chewing tobacco carry explicit cancer warnings, FDA-approved nicotine replacement therapies (NRT) like patches and gum generally do not, as they are not classified as carcinogens.  Warning Label Differences

• Cigarettes and Chewing Tobacco: These products must carry federally mandated warnings explicitly stating they cause cancer (e.g., mouth, lung, or pancreatic cancer) due to the presence of over 70 known carcinogens like tobacco-specific nitrosamines (TSNAs), arsenic, and formaldehyde.
  
• Nicotine Patches and Gum: As medical products, their labels focus on safety and usage instructions. Standard warnings typically address addiction, heart rate increases, or use during pregnancy, but they do not include "causes cancer" because medicinal nicotine does not contain the toxic tar or combustion byproducts found in tobacco. 
  

 Nicotine and Cancer Risk

• Not a Known Carcinogen: Major health bodies, including the International Agency for Research on Cancer (IARC), do not classify nicotine as a carcinogen.
  
• Promoter vs. Cause: While nicotine doesn't start cancer (initiation), some research suggests it may act as a "tumor promoter," potentially speeding up the growth of existing cancer cells or interfering with certain treatments.
  
• Safety of Replacement: The Centers for Disease Control (CDC) and Johns Hopkins Medicine state there are no known studies linking NRT use to cancer in humans, and emphasize that using NRT is significantly safer than continued smoking. 
  

[andy06shake]

Scientific and health organizations distinguish between the risks of nicotine itself and the carcinogenic compounds found in tobacco products. Whilecigarettes and chewing tobacco carry explicit cancer warnings, FDA-approved nicotine replacement therapies (NRT) like patches and gum generally do not, as they are not classified as carcinogens.  Warning Label Differences

• Cigarettes and Chewing Tobacco: These products must carry federally mandated warnings explicitly stating they cause cancer (e.g., mouth, lung, or pancreatic cancer) due to the presence of over 70 known carcinogens like tobacco-specific nitrosamines (TSNAs), arsenic, and formaldehyde.
  
• Nicotine Patches and Gum: As medical products, their labels focus on safety and usage instructions. Standard warnings typically address addiction, heart rate increases, or use during pregnancy, but they do not include "causes cancer" because medicinal nicotine does not contain the toxic tar or combustion byproducts found in tobacco. 
  

 Nicotine and Cancer Risk

• Not a Known Carcinogen: Major health bodies, including the International Agency for Research on Cancer (IARC), do not classify nicotine as a carcinogen.
  
• Promoter vs. Cause: While nicotine doesn't start cancer (initiation), some research suggests it may act as a "tumor promoter," potentially speeding up the growth of existing cancer cells or interfering with certain treatments.
  
• Safety of Replacement: The Centers for Disease Control (CDC) and Johns Hopkins Medicine state there are no known studies linking NRT use to cancer in humans, and emphasize that using NRT is significantly safer than continued smoking. 
  

Nicotine itself may not be classified as a carcinogen, but it's still highly addictive and can also act as a "tumor promoter."

[quintessentone]

Scientific and health organizations distinguish between the risks of nicotine itself and the carcinogenic compounds found in tobacco products. Whilecigarettes and chewing tobacco carry explicit cancer warnings, FDA-approved nicotine replacement therapies (NRT) like patches and gum generally do not, as they are not classified as carcinogens.  Warning Label Differences

• Cigarettes and Chewing Tobacco: These products must carry federally mandated warnings explicitly stating they cause cancer (e.g., mouth, lung, or pancreatic cancer) due to the presence of over 70 known carcinogens like tobacco-specific nitrosamines (TSNAs), arsenic, and formaldehyde.
  
• Nicotine Patches and Gum: As medical products, their labels focus on safety and usage instructions. Standard warnings typically address addiction, heart rate increases, or use during pregnancy, but they do not include "causes cancer" because medicinal nicotine does not contain the toxic tar or combustion byproducts found in tobacco. 
  

 Nicotine and Cancer Risk

• Not a Known Carcinogen: Major health bodies, including the International Agency for Research on Cancer (IARC), do not classify nicotine as a carcinogen.
  
• Promoter vs. Cause: While nicotine doesn't start cancer (initiation), some research suggests it may act as a "tumor promoter," potentially speeding up the growth of existing cancer cells or interfering with certain treatments.
  
• Safety of Replacement: The Centers for Disease Control (CDC) and Johns Hopkins Medicine state there are no known studies linking NRT use to cancer in humans, and emphasize that using NRT is significantly safer than continued smoking. 
  

Well, I was just reading about vaping nicotine and it mentioned that other harmful chemicals were created from it being heated.

"Other harmful effects: Although not carcinogenic, nicotine can still promote cancer progression through mechanisms like stimulating cell proliferation, angiogenesis, and immune system modulation—particularly in the presence of existing cancer cells. 

"Several lines of evidence indicate that nicotine may contribute to the development of cancer. Evidence from experimental in vitro studies on cell cultures, in vivo studies on rodents as well as studies on humans inclusive of epidemiological studies indicate that nicotine itself, independent of other tobacco constituents, may stimulate a number of effects of importance in cancer development (5, 6)."

https://pmc.ncbi.nlm.nih.gov/articles/PMC4553893/

It seems to me that we really don't know very much about the compounds of nicotine and how it reacts with the body. Then again it seems we do.

[Knows]

Nicotine itself is well-established as the primary addictive substance in tobacco.

Nicotine is ignorantly blamed. Made up nonsense.  All scientific tests show Nicotine alone is  not the main cause of tobacco addiction.  I've chewed a little nicotine gum for over a year with no symptoms of addiction. I should know. 

substantial evidence exists to suggest that nicotine's reinforcing effects alone are not sufficient to account for the intense addictive properties of tobacco smoking and the high relapse rates among smokers after quitting even when provided nicotine in forms other than tobacco.[sup]8–16[/sup] Further evidence that tobacco dependence entails more than addiction to nicotine includes the drug's limited ability to induce self-administration in animals;[sup]17[/sup] [sup]18[/sup] lack of positive mood effects of pure nicotine in abstinent smokers;[sup]19–21[/sup] lack of findings that nicotine in any other form than tobacco was preferred to placebo in normal smokers;[sup]22[/sup] [sup]23[/sup] de-nicotinised cigarettes were as effective as regular cigarettes, and more than nicotine in any other delivery mode, in relieving withdrawal and craving;[sup]24–27[/sup] and essential role of non-nicotine factors in cigarette addiction.[sup]24[/sup] [sup]28[/sup]
The release of tobacco industry documents in the 1990s and investigation by the US Food and Drug Administration (FDA) brought to light tobacco manufacturers’ research and development of the use of additives and ingredients besides nicotine which led to the increased appeal, attractiveness and addictiveness of products
 

lack of findings that nicotine in any other form than tobacco was preferred to placebo in normal smokers;

[andy06shake]

Nicotine is ignorantly blamed. Made up nonsense.  All scientific tests show Nicotine alone is  not the main cause of tobacco addiction.  I've chewed a little nicotine gum for over a year with no symptoms of addiction. I should know. 

lack of findings that nicotine in any other form than tobacco was preferred to placebo in normal smokers;

Cool story.

And yet you keep chewing the stuff "for over a year"....