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I personally think that the overuse of Tylenol is bad for people. People are under the impression it is harmless and it is in too many medications, lots of people are unaware they are using more than they should be.
As to the risk factor, it probably has some basis to it, but the article was edited a year later to show that it is just opinion.
My concern with tylenol is the effect on the liver. That is not an issue if you take it once in a while, but I know lots of people that were taking it regularly for pain...and they had pain in the area from inflammation and had their gallbladers removed...maybe possibly because of that inflammation. But it may not be related either, even though there were no actual stones. The liver getting compromised can cause lots of problems, including raised lipids in the blood because it actually is important with lipid metabolism.
Ibuprofen is harder on the kidneys. I actually experienced that problem when I tried taking it for a sore back years ago for two weeks at the prescribed dose. When my kidneys started hurting, I went to the doctors and he mentioned it was most likely the ibuprofen that triggered it. Haven't taken one since then, the kidney jumping around stopped after a few days of stopping taking it...so the doctor was right.
I got constipated off of anexsia and other similar meds the doctors prescribed, and that became a real issue even at occasional use That contained tylenol. So I rarely used the pills because of that...so I tried tylenol and that does nothing for pain for me, so I figured it was all the opiates that helped the pain in the Anexsia.
Ibuprofen worked but I quit that and dealt with the pain for a while till my kidneys stopped jumping.
I now just take one three hundred twenty five milligram aspirin which works great for me. I used to take thee aspirin years ago, but that is when they were hundred milligrams, and I found out the hard way that they changed the dosage years back to three twenty five mg so I figured I would just take one if needed, or for a mild pain, one baby aspirin occasionally works just fine. I guess in Europe the aspirins are still one hundred mgs....that increase made aspirin more dangerous at the dose they say is two pills here in America. I think they did that to make us buy the Tylenol which cost more and had a patent to protect it years ago...Rey's syndrome from is bad. They sabotaged aspirin as a medicine years ago. But it didn't take me long after I discovered the change to fix the issue.
I actually had problems with issues similar to salicylate poisoning when I peeled a pile of poplar logs that had been sitting for a year to cut into firewood with no gloves on. the bark had gotten slimey, so I peeled the bark off and stacked the wood after splitting it. It only lasted for about a week or two, but I wasn't sore anywhere I usually had pain when I did it for a few days anyway. but at the end, I had issues in my gut and maybe liver area and looked it up. and I refrained from taking aspirin for months till my levels went down. Those pesky little microbes actually turn salicylates into aspirin I read. The poplar leaves actually can be made into aspirin using alcohol. But I think that birch leafs would be better because it also creates the chaga terpine chemistry to go along with the aspirin with the alcohol extraction... from betulate in the tree. Evidently, that chaga mushroom creates alcohol or something to make the acid form.
Not related to the butyric acid found in butter at all.