BREAKING NEWS: Slovak Government Official Claims DNA in Vaccines

[Kwaka]

They have compiled vague and unattributed disinformation together with an audit of grant money source, and assumed that is evidence.

The evidence does stop at the money trail. The following link is to a 75 page pdf file that Eco Health Alliance provided to DAPRA in 2018.

Project DEFUSE: Defusing the Threat of Bay-borne Coronaviruses

It goes through in detail just what exactly Eco Health Alliance aims to achieve in working with the Wuhan Institute of Virology. DAPRA said no to funding this proposal due to its Gain Of Function work. With the way things turned out, Eco Health Alliance got the money from somewhere to go ahead with its plans.

[chr0naut]

The evidence does stop at the money trail. The following link is to a 75 page pdf file that Eco Health Alliance provided to DAPRA in 2018.

Project DEFUSE: Defusing the Threat of Bay-borne Coronaviruses

It goes through in detail just what exactly Eco Health Alliance aims to achieve in working with the Wuhan Institute of Virology. DAPRA said no to funding this proposal due to its Gain Of Function work. With the way things turned out, Eco Health Alliance got the money from somewhere to go ahead with its plans.

Please read the document you provided and note that it says in the executive summary, "... (these use bat-SARSr-CoV backbones, not SARS-Cov, and are exempt from dual-use and gain of function concerns)" which is directly contradictory to points 1 to 3 of the "reasons for rejection" in the DRASTIC summation of what they are calling 'DARPA's rejection'.

The DRASTIC summary does mention that two out of the three DARPA reviewers approved that the funding could go ahead, and that the submission was actually not rejected, but was put aside "at that time", while further investigation was ongoing.

It is clear that the Biological Technologies office of DARPA reviewing did not bother to read, or did not understand the specifics of the funding request by EcoHealth Alliance.

Defuse Project Rejection by Darpa

EcoHealth Alliance Response to False Statements About an Unfunded Grant Proposal

There is no evidence that EcoHealth Alliance pursued dual-use/GOF research under other funding.

The fact that there were no signs of SARS-CoV-2 virus, nor any traces of its existence, nor any organisms or staff carrying antibodies, in the lab at Wuhan in 2019-2020 time rame, indicates that the virus just wasn't there. If the virus wasn't there, it could not have spread from there. Nor could it have been created there from GOF research if the virus just wasn't there.

[Kwaka]

The fact that there were no signs of SARS-CoV-2 virus, nor any traces of its existence, nor any organisms or staff carrying antibodies, in the lab at Wuhan in 2019-2020 time rame, indicates that the virus just wasn't there. If the virus wasn't there, it could not have spread from there. Nor could it have been created there from GOF research if the virus just wasn't there.

There are no signs of SARS-CoV in the Defuse Project? Ha Ha Ha. Even has the Furin Cleavage getting spliced in. Appears this was one of the first mutations to change out as took off around the world.
 

There is no evidence that EcoHealth Alliance pursued dual-use/GOF research under other funding.

All the doctors included and what they where working on is described. I don't know who paid them, someone did as they still kept their jobs during these times.
 

dual-use

This kind of language comes across as a legalize cognitohazzard. It does not make sense to expect that nature can be so easily contained. Especially when getting into the depths of the work being done. Maybe some minor changes along the way. As for the overall direction: Gain of function work on Bat Coronavirus that bind to ACE2 receptors and has a Furin cleavage site.

[Kwaka]

Boris Johnson is calling it a Lab Leak in a colorful way with his latest book.

[chr0naut]

There are no signs of SARS-CoV in the Defuse Project? Ha Ha Ha. Even has the Furin Cleavage getting spliced in. Appears this was one of the first mutations to change out as took off around the world.

I did not say there was no speculation about of SARS-like viruses in the DEFUSE project (which was never funded nor implemented). What I said that there was no signs or indications of the presence of SARS-CoV-2 virus in the Wuhan lab, or in the people who worked there, in the time frame of 2019-2020.

The DEFUSE proposal mentioned the bat-SARS-CoVr virus was being used very specifically, and not SARS-CoV, and this was to avoid the possibility of gain of function/dual-use issues.
 

All the doctors included and what they where working on is described. I don't know who paid them, someone did as they still kept their jobs during these times.
 
This kind of language comes across as a legalize cognitohazzard. It does not make sense to expect that nature can be so easily contained. Especially when getting into the depths of the work being done. Maybe some minor changes along the way. As for the overall direction: Gain of function work on Bat Coronavirus that bind to ACE2 receptors and has a Furin cleavage site.

But the fact that bats can't catch SARS-CoV-2 says something about the genetic origins of the virus.

If function was added to a bat virus to allow it to infect humans by the insertion of the furin receptor in human ACE2, then it would also have retained some infectiousness in bats, as co-hosts, which it doesn't have.

But furin cleavage in ACE2 occurs with other coronaviruses and isn't as weird as you have been led to believe. It could totally arise in nature and has done so previously in coronaviruses, and those affecting other animals.

Furin cleavage sites in the spike proteins of bat and rodent coronaviruses: Implications for virus evolution and zoonotic transfer from rodent species

All the human specificity of furin cleavage in human ACE2 says, is that the SARS-CoV-2 virus arose specifically adapted for humans. It arose in humans - specifically. It infects humans - specifically.

Bats simply cannot be the source of SARS-CoV-2, evidence by their inability to host the virus. The lab-leak theory has vanishingly small likelihood.

Doctor Rand Paul who implied that the DEFUSE proposal was about GOF, is an ophthalmologist, not a geneticist, biochemist or virologist. He is also primarily a politician, a member of a party who presided over a disastrous mishandling of an infectious disease outbreak (1,168,021 dead in two years - not to mention the deaths caused in the rest of the world by not containing the disease), and who are trying to put the blame elsewhere but on themselves.

Remember there were other very similar disease outbreaks, SARS, EBOLA, H1N1 and Zika, in the USA during the Obama administration. How many US citizens died then?

[chr0naut]

[Video: https://www.youtube.com/watch?v=68tYsBI0Uyc]

Boris Johnson is calling it a Lab Leak in a colorful way with his latest book.

Honestly, how would Boris Johnston know anything better than any other politician? I'm also fairly sure that the government under My Johnston was exposed several times for mishandling their response to the disease. He has good motivation to deflect away from the truth.

However, most authoritative and credentialled expert commentators say that the virus most likely arose naturally. That hasn't changed.

It just makes the politicians look even more untrustworthy, IMHO.

[Kwaka]

What I said that there was no signs or indications of the presence of SARS-CoV-2 virus in the Wuhan lab, or in the people who worked there, in the time frame of 2019-2020

Did you miss that part where Shi Zhengli was called the 'Bat Lady'. Spent her career studying bat viruses. And now you expect that culmination of her life's work does not exist as China says no to any public inquiry. Ecohealth Alliance where still a big stakeholder at the Wuhan lab.
 

But the fact that bats can't catch SARS-CoV-2 says something about the genetic origins of the virus.

It also says you need to do more homework to really appreciate what Defuse is about. The viral gene started in Bats, well proven with the genetic sequencing done at the start of the pandemic.

What was changed in the lab was around the spike protein. This is the part of the virus that latches onto the cell wall of its new home. Once this was changed to attract to humans, it lost its attraction to bats.

The furin cleavage site was another addition, with results being a more pathogenic virus. This feature also exists in AIDS. Good thing this addition mutated out early as viruses adapt, change and evolve. Every flu session has different strains.
 

Honestly, how would Boris Johnston know anything better than any other politician?

Just a heads up as another brink in the wall tumbles down.

[chr0naut]

Did you miss that part where Shi Zhengli was called the 'Bat Lady'. Spent her career studying bat viruses. And now you expect that culmination of her life's work does not exist as China says no to any public inquiry. Ecohealth Alliance where still a big stakeholder at the Wuhan lab.
 
It also says you need to do more homework to really appreciate what Defuse is about. The viral gene started in Bats, well proven with the genetic sequencing done at the start of the pandemic.

What was changed in the lab was around the spike protein. This is the part of the virus that latches onto the cell wall of its new home. Once this was changed to attract to humans, it lost its attraction to bats.

Once it lost its infectiousness to bats, the changed virion would have to have fairly quickly infected another host species (viruses oxidise and break down, usually in hours). In this specific case, the host would have been either humans or humanized mice (since bats could no longer host the virus). In both cases, surviving hosts would carry antibodies to the virus after the fact of an infection.

The presence of antibodies is a sure indicator of exposure to a novel virus.

In the lab at Wuhan, when it was tested by Chinese and international authorities in several subsequent sweeps, there were no antibodies detected in either workers or in test animals. Nor was the live virus genomic strand directly detected within the facility boundaries, airborne, on surfaces, in wastes, vents, filters or drains.

Of course, this could be explained by lab cleanliness procedures, secure destruction of the experimental hosts, and strong isolation between the infection and staff. However, if these things were the reason the virus or residue wasn't found, then they are also the reason that a lab leak did not occur.

The furin cleavage site was another addition, with results being a more pathogenic virus. This feature also exists in AIDS.

AIDS is a disease symptomology. HIV is the virus (family) that causes AIDS in humans.

Although it sounds all doom-porny and everything, it is irrelevant that HIV utilizes furin cleavage, because furin cleavage is not unique to those viruses and no-one put some of the HIV genes into SARS-CoV-2.

I can be sure of this because (contrary to what has been touted by anti-vax/plandemicists), there are no identical gene sequences at all between the two families of virus. SARS-CoV-2 has nothing at all in common genomically with HIV. You can verify this for yourself by comparing the two genomes in SLAM.

Good thing this addition mutated out early as viruses adapt, change and evolve.

Furin cleavage is a function intrinsic to the spike protein in extant strains of SARS-CoV-2. It isn't really separate. It remains a feature.

A mutated version of SARS-CoV-2 was produced in the lab to test if theories about furin cleavage were as believed. This mutated strain, without furin cleavage, was still infectious, but notably less infectious. All noted extant strains are, however, more infectious, not less, so furin cleavage is still part of those strains.

Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis (please read this paper to understand it, and don't just stop at the title).

Every flu session has different strains.

Influenza viruses, coronaviruses and HIV, are all very different families of virus.

Furin cleavage both enhances penetration of cell membranes by ACE2 binding and also facilitates many biochemic processes within the cell via furin activation:

Furin Cleavage Sites in Viral Pathogenesis and Host Interaction

As previously posted, the presence of a furin cleavage site is a feature of other coronaviruses. It is not unique to either SARS-CoV-2 nor to humans:

Furin cleavage sites in the spike proteins of bat and rodent coronaviruses: Implications for virus evolution and zoonotic transfer from rodent species
 

Just a heads up as another brink in the wall tumbles down.

I think you may have meant another 'brick' or 'chink' in the wall tumbling down.

brink - definition

[Kwaka]

Once it lost its infectiousness to bats, the changed virion would have to have fairly quickly infected another host species (viruses oxidise and break down, usually in hours).

This paper is by the Bat Lady from 2013. Had a long time to work on this part of the process.

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
 

The presence of antibodies is a sure indicator of exposure to a novel virus.

How did China go in locating patient 0 and identifying the source? All quite from here. How many lab workers carry antibodies to all the products they work on? Occasional workplace accidents or consent to some experiment.

How you think a lack of evidence proves something also puts a lot of weight on China. For now they still seam happy with the progress on biological research as Shi Zhengl still has a job. Some of the local journalists able to share what they could about the situation got hit hard by the CCP, jail time. The CCP delayed any independent investigations for a while. Gave them time to come up with squeaky clean paperwork while removing the evidence, as much as they could.
 

However, if these things were the reason the virus or residue wasn't found, then they are also the reason that a lab leak did not occur.

Yes, good deduction for an intentional release.
 

it is irrelevant that HIV utilizes furin cleavage,

No. This is part of the genetic variation that dismisses a natural origin. In my interpretation of  a cleavage, it acts like a spring and causes the shape of the protein to change. In HIV, its cleavage allows it to attack immune cells and cause some damage. Part of how the immune system declines with AIDS..Strange hows the Queensland University attempt to develop a vaccination tested positive for HIV in the participants..

In the complexity of life, different ways things can cleave. The similarity with how HIV cleaves is one that stood out in the early days. With the state of science, not surprised some still support the zoonotic theory. There was no BLAST data at the time it broke out indicating a furin cleavage in the bat corona viruses stored there. If there was, this issue would of been solved a long time ago. There where some small matches with HIV.

One recent and good lesson on the nature of virology:

EPISODE 416: DIDIER RAOULT UNCENSORED
 

anti-vax/plandemicists

Eugenic/profiteer

[UltraBudgie]

Why does this thread remind me an endless maze of rational "fact-based" argumentation? Does this approach even work any more, cf., the Kennedy assassination, and 9/11? Post-truth pastiche as a preformative art. I guess that's all that's left, outside the church or laboratory.