05-14-2024, 11:30 AM
Wow! There on the path now!
In the early 2000s, a colleague of the research team at Western University noticed a protein in mice which caused difficulty in muscle function when abnormal. The team was able to find there is a very similar protein in humans, which can reverse the process or at least pause it from further deterioration. When modified with the protein, the mice would die within 10 to 20 days, but with the second protein, they were still alive at 18 weeks.
“The importance of the report today is identifying that this protein exists, showing it actually works on two different animal models and providing some insight into how it would work,” says Strong. ‘The important piece then comes over the next three to five years.”
Researchers have spent the past 15 or so years working on this project, and the first clinic for ALS was established around the 1980s. The risk of getting ALS is around one in 300 or one in 400, averaging to around two per 100,000.
I am so stoked for this to develop further. ALS is a tragic affliction... especially considering how quickly someone can lose their motor functions and their independence.
Nice Find... great news!
I am a harsh critic of "research" activities because of how easily they are abused for profit... and then this! Excelsior!
It just goes to show you... Never give up!
In the early 2000s, a colleague of the research team at Western University noticed a protein in mice which caused difficulty in muscle function when abnormal. The team was able to find there is a very similar protein in humans, which can reverse the process or at least pause it from further deterioration. When modified with the protein, the mice would die within 10 to 20 days, but with the second protein, they were still alive at 18 weeks.
“The importance of the report today is identifying that this protein exists, showing it actually works on two different animal models and providing some insight into how it would work,” says Strong. ‘The important piece then comes over the next three to five years.”
Researchers have spent the past 15 or so years working on this project, and the first clinic for ALS was established around the 1980s. The risk of getting ALS is around one in 300 or one in 400, averaging to around two per 100,000.
I am so stoked for this to develop further. ALS is a tragic affliction... especially considering how quickly someone can lose their motor functions and their independence.
Nice Find... great news!
I am a harsh critic of "research" activities because of how easily they are abused for profit... and then this! Excelsior!
It just goes to show you... Never give up!
