05-11-2026, 07:01 PM
(05-11-2026, 02:52 PM)Knows Wrote: Hint. Kind of fits with Dr Ardis's revelations.AI Overview Research into synthetic venom, often created via venom gland organoids or chemical synthesis, focuses on developing faster, more effective antivenoms and discovering new therapeutic drugs. Scientists have successfully grown "mini-glands" from snakes that produce venom almost identical to the real thing. [1, 2, 3, 4, 5]Here are the key areas of development:
Note on the term "Plasmoids": In the context of biological research, "plasmoids" is likely not a standard term, though the research involves plasma inhibitors (inhibitors found in the blood of immune snakes) and venom organoids. The results indicate that the term "plasmoid" is generally used in physics (ionized gas) or, colloquially, for fictional shapeshifting entities. [1, 2, 3, 4, 5]
- Synthetic Venoms via Organoids: Researchers use stem cell technology to create 3D organoids (mini-glands) from various snake species to produce venom in laboratory settings. This allows for studying venom without relying on milking live snakes, which is safer and more reliable.
- Synthetic Inhibitors and Antivenom:
- Engineered Nanoparticles (NPs): Researchers have developed synthetic polymer nanoparticles engineered to bind to and neutralize toxic proteins in elapid snake venom, offering a potential stable, low-cost, and broad-spectrum alternative to traditional antivenom.
- Varespladib (LY315920): A synthetic small molecule that inhibits phospholipase A2 (PLA2) enzymes, which are responsible for tissue destruction in snakebites.
- Synthetic Antibodies: Scientists have created synthetic antibodies that can neutralize a major class of neurotoxins, providing a potential broad-spectrum treatment.
- Medical Applications: Synthetic peptides derived from snake venom components (such as RGD domains) are used for developing drugs targeting platelet aggregation.
- Mechanism of Action Study: Molecular dynamics simulations have shown that synthetic venom peptides can spontaneously form pores in cell membranes, causing cell death (necrosis). [1, 2, 3, 4, 5, 6, 7]
As you noted, a 'plasmoid' is a term used to describe 'a boundary state of matter between two discrete energy/state levels' in physics.
The different, but similar sounding, term used in relation to biology is a 'plasmid'.
A plasmid is a closed loop of DNA that is not part of any chromosome, but that are found inside cells (usually not in their nucleus - a term also used in physics for something else, LOL). As DNA is a long chain molecule, disconnected fragments can sometimes connect their ends to themselves in a loop, forming a plasmid.
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