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Reducing Alzheimer's Risk with Viagra? - Printable Version

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Reducing Alzheimer's Risk with Viagra? - Maxmars - 03-25-2024

The onset and development of Alzheimer's can be a tragic and devastating thing to experience.  The neurodegenerative disease has been said to cause brain shrinkage, brain cell death, and worsening dementia ... and it's no wonder we cringe inside when we know of the harm it has done to people everywhere.

A certain medication has surfaced in recent years, Viagra (Sildenafil) has been popularized because of the increasingly successful use in treatments of sexual disfunction (in both males and females.)  But it is also useful with pulmonary arterial hypertension, Raynaud's Phenomenon (numbness in certain body parts,) and now maybe (hopefully) something further:

From ScienceAlert: Huge Study Confirms Viagra Cuts Alzheimer's Risk by Over 50%
 

An FDA-approved pharmaceutical used to treat erectile dysfunction could soon be recommended as a therapy for decreasing the risk of Alzheimer's disease.

By analyzing medical insurance data alongside a laboratory investigation on the genetic and neurological effects of sildenafil – a drug sold commonly under the brand name Viagra – researchers in the US have validated the medication's potential in keeping critical proteins in nerve cells from tangling into a deadly mess.

Studies have repeatedly demonstrated enzyme blockers called phosphodiesterase (PDE) inhibitors not only have an ability to promote blood flow in the penis, but could prevent the neurodegeneration responsible for dementia.



Here's to hoping we can drastically reduce the onset of brain maladies with this new approach...


RE: Reducing Alzheimer's Risk with Viagra? - Tecate - 05-13-2024

As a long term Paramedic I have seen numerous patients from their initial diagnosis to their end stage. It’s indeed a terrible disease process and if sildenafil can reduce the chances of acquiring it then why not?

PDE Inhibitors, like many other types of drugs are usually found to be useful and effective in helping treat other illnesses and issues.
Some antidepressants aid in smoking cessation treatment for example.

Hopefully this treatment becomes successful and they can start working on other processes like ALS, MS, etc.

Tecate