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mRNA Pancreatic Cancer vaccine: Maybe?
#1
Encouraging news regarding a patient who reportedly appears to have "beaten" pancreatic cancer.

From Fox: Experimental vaccine for common cancer shows potential in clinical trial

The magazine is retell of an article from Nature: RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer

Of course, making tabloid declarations of a distinctly non-vaccine-like technology which is mRNA-based, might be premature in Phase 1... but I have no doubt this will be massaged into something to get those investment dollars flowing.  Look for it on the marketweb... under "Cure for cancer!"  (I notice they are still trying to call mRNA tech a "vaccine" rather than a direct recoding of DNA-based life processes.)

Ultimately, there is statistical evidence that the treatment offered did create an outcome where the body's own immune system began to recognize the cancer and deal with it as any other such element within the body.  That's sounds good... I think.

While I don't recommend hooking all our hopes onto any single wagon... it's potentially good news... who knows?  Maybe they've actually found something to help... rather than some multi-year Bandaid treatment course that only drains the wealth from the patient, and leaves them exactly as they are... sick and in need.

Oooh... that last sounded cynical, no?  Apologies...

[edit to fix title... thanks Byrd!]
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#2
(02-21-2025, 03:09 PM)Maxmars Wrote: Encouraging news regarding a patient who reportedly appears to have "beaten" pancreatic cancer.

From Fox: Experimental vaccine for common cancer shows potential in clinical trial

The magazine is retell of an article from Nature: RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer

Of course, making tabloid declarations of a distinctly non-vaccine-like technology which is mRNA-based, might be premature in Phase 1... but I have no doubt this will be massaged into something to get those investment dollars flowing.  Look for it on the marketweb... under "Cure for cancer!"  (I notice they are still trying to call mRNA tech a "vaccine" rather than a direct recoding of DNA-based life processes.)

Ultimately, there is statistical evidence that the treatment offered did create an outcome where the body's own immune system began to recognize the cancer and deal with it as any other such element within the body.  That's sounds good... I think.

While I don't recommend hooking all our hopes onto any single wagon... it's potentially good news... who knows?  Maybe they've actually found something to help... rather than some multi-year Bandaid treatment course that only drains the wealth from the patient, and leaves them exactly as they are... sick and in need.

Oooh... that last sounded cynical, no?  Apologies...

Hopeful news, Max...but the title should be changed to "pancreatic cancer" (which killed a friend of mine.)

There are many different types of cancers, which is why there's no blanket "cancer cure."
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#3
Might go off on a rant here my Dad died of Pancreatic cancer because he was a tough SOB he kept feeling pain and finally at one point went to the hospital and the doctor discovered how sick he was. Even then the man had a nerve block done for the pain and didn't tell his family till it was obvious he was sick. 

If there is a 1/100th chance 1/1000th chance this works

I guarantee there are cancer patients and their families who would have tried anything.

So how about fast-tracking this and giving this option to terminal patients and their families?
His mind was not for rent to any god or government, always hopeful yet discontent. Knows changes aren't permanent, but change is ....                                                                                                                   
Professor
Neil Ellwood Peart  
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