03-14-2026, 01:37 PM
Scientists Discover Simple Trick That Boosts mRNA Therapy Delivery 20-Fold
LNPs (liquid nano-particles) were the 'component' that delivered the Covid treatment to change the cell functions of billions of human beings... when it was launched there were many glory cries of technological success and how this might treat cancers some day...
Some difficulties were encountered though... the LNPs actually were not as effectively measured as in the laboratories rich substrates... in the human body they under-performed by a tune of 50-85%... still useful...
but by now delivering the LNPs in a substrate of rich amino acids... boom baby!
Good, bad? I am no one to say... it's all so complicated, no?
Surely I can't appreciate this article as much as some of you...
Enjoy!
Quote:(a '20-fold' 'delivery' increase?)
.... discovered that giving three common amino acids together with LNPs can dramatically improve delivery. The amino acids methionine, arginine, and serine increased mRNA delivery by as much as 20 times and raised CRISPR gene editing efficiency from about 25 percent to nearly 90 percent after a single treatment.
LNPs (liquid nano-particles) were the 'component' that delivered the Covid treatment to change the cell functions of billions of human beings... when it was launched there were many glory cries of technological success and how this might treat cancers some day...
Some difficulties were encountered though... the LNPs actually were not as effectively measured as in the laboratories rich substrates... in the human body they under-performed by a tune of 50-85%... still useful...
but by now delivering the LNPs in a substrate of rich amino acids... boom baby!
Good, bad? I am no one to say... it's all so complicated, no?
Surely I can't appreciate this article as much as some of you...
Enjoy!
