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Newest treatment for Schizophrenia in 30 years
#7
Looks like a banger:
Quote:The primary efficacy measure was the change from baseline in the Positive and Negative Syndrome Scale (PANSS) total score at week 5. The PANSS is a 30-item scale that measures symptoms of schizophrenia. Each item is rated by a clinician on a seven-point scale. In both studies, the participants who received Cobenfy experienced a meaningful reduction in symptoms from baseline to Week 5 as measured by the PANSS Total Score compared to the placebo group.
 
The prescribing information includes warnings that Cobenfy can cause urinary retention, increased heart rate, decreased gastric movement or angioedema (swelling beneath the skin) of the face and lips. Cobenfy is not recommended for patients with mild hepatic (liver) impairment. It should not be used in patients with known hepatic impairment. There is also a risk of liver damage. Patients should stop using Cobenfy if experiencing signs or symptoms of substantial liver disease (including yellowing of the skin or the white part of the eyes, dark urine and unexplained itching). Cobenfy is substantially excreted by the kidney and is not recommended in patients with moderate to severe renal impairment. 
 
Cobenfy should not be prescribed to patients with urinary retention, moderate or severe kidney or liver disease, gastric retention, untreated narrow-angle glaucoma or a history of hypersensitivity to either Cobenfy or its components.
 
The most common side effects of Cobenfy are nausea, indigestion, constipation, vomiting, hypertension, abdominal pain, diarrhea, tachycardia (increased heartbeat), dizziness and gastroesophageal reflux disease.

https://www.fda.gov/news-events/press-an...izophrenia

It's taken twice a day, with an estimated annual list price of $22500. I suppose it may be better than Zombieland though. Or actually having to face the demons.
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RE: Newest treatment for Schizophrenia in 30 years - by UltraBudgie - 09-29-2024, 11:17 AM

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