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Newest treatment for Schizophrenia in 30 years
#2
THE SCIENTIFIC DOCTOR

WHEN I went to the scientific doctor
I realised what a lust there was in him to wreak his so-called
science on me
and reduce me to the level of a thing.
So I said: Good-morning! and left him.

   - D.H. Lawrence

(09-27-2024, 06:51 PM)Maxmars Wrote: This drug wasn't developed by Bristol-Myers Squibb (BMS)… it was developed by a company called KARUNA THERAPEUTICS, which  BMS purchased for 14 Billion dollars recently.  Since the purchase, every major media company has used words like "revolutionary," "breakthrough," and "novel"...  but not before, when it was a Karuna product... owning the press can be a wonderful thing for business, no?

Karuna was spun up specifically to develop xanomeline therapy for psychiatric use:
Quote:In the 1990s, Eli Lilly and Company tried to develop xanomeline as a treatment for Alzheimer’s disease, but the gastrointestinal side effects were too difficult to manage. Andrew Miller, then an executive at PureTech Health, licensed xanomeline in 2012 and founded Karuna to develop the treatment. Karuna solved the side effect problem by adding trospium, a muscarinic antagonist, to block xanomeline from the muscarinic receptors outside the brain. Trospium does not cross the blood-brain barrier, preserving xanomeline’s beneficial activity.
https://cen.acs.org/pharmaceuticals/drug...eb/2024/09

Here's the original paper from 2008. The initial research was sponsorted by Lilly, BMS, and others:
Quote:Supported by a grant from Eli Lilly.Dr. Shekhar has received grant support from NIH, Eli Lilly, Pfizer, GlaxoSmithKline, Johnson & Johnson, Bristol-Myers Squibb, and Wyeth. Dr. Potter is an employee of Merck. Drs. Dubé, Felder, Mallinckrodt, and McKinzie and Mr. Lieneman are employees of Eli Lilly. Mr. Bymaster is a former advisor for Eli Lilly.
https://psychiatryonline.org/doi/10.1176...8.06091591

While I am cynical of allopathic medicine in a way I believe to be appropriate, I am also hopeful for anything that might better help those who suffer.

edit: ps i think im getting the hang of this place ive just got to capitalize and proofread and lippyserve rationlism! hahah! Tumble
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Messages In This Thread
RE: Newest treatment for Schizophrenia in 30 years - by UltraBudgie - 09-27-2024, 08:17 PM

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